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Jess25

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  • "Jess25" started this thread

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Reg: Jun 29th 2014

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Friday, July 4th 2014, 8:14pm

Confused!

Please can someone tell me some info on the process of pgd from the first appointment and what happens from then on? It's all very confusing and google doesn't tell us much info :) we have decided pgd is the best option but haven't started anything yet. Would be so grateful if someone could give me some more info
Jess.

Onewish

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    United Kingdom

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Reg: Jul 24th 2010

Location: Suffolk

Children: one beautiful daughter at last!

What's Up?
Will we, won't we...?

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Friday, July 4th 2014, 8:26pm

Hi there, i have never had this procedure myself so no idea, but i just went onto the hfea website and they have a fair bit of info on this. Hope this helps. X

TTC = 10 yrs +
4 ICSI 1 FET
4th ICSI - Gennet Prague BFP!!!!
:girl: shes arrived!!! 1.6.14

My Diary - Onewish's ICSI journey

Jess25

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Friday, July 4th 2014, 9:21pm

Thanks for your reply, I have looked on some different websites but none of them seem to tell you about the actual process.

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Saturday, July 5th 2014, 12:34pm

Hi Jess, I can't find my proper notes so in a nutshell and withouth months:

You have to bear in mind that we came from another country so had to start everything again from scratch.

went to GP late 2007 or early 2008
went to colon cancer specialist 2008 (probably not applicable for you)
went to genetic counsellor for initial appoinment 2008
genetic counsellor blood test to confirm mutation 2008
genetic counsellor a couple more times including advice on PGD and other options (I remember being quite frustrated at this point but they were really quite nice and not everyone knows as much about PGD as we did by that point)
being referred to fertility clinic (finally!!) 2009
initial meeting with PGD nurse at fertility clinic
basic fertility tests to see if we can at all be helped with ICSI-PGD
blood test from us and relatives 2009 to make PGD probes
loooooong wait for probes to be ready, more than a year but I heard they can be quicker nowadays.
Appointments with fertility and PGD specialists (we were proactive here as they wanted a joint meeting but could never organise this so we said we are happy to go twice just let us start please)
about to start in 2010 April when lovely news that we got approved for funding for 1 cycle
May 2010 PGD cycle successful!!!
2011 Daughter born :-)

The whole thing was a lot easier for our second daughter as the probes were ready and we were self funded so we could start in a couple of month after telling them, although after our BFN in the 2nd cycle we waited 6 months (rather than the minimum of 3 months wait) to be amotionally ready.

I might be far fetched here as I don't even know how many children you are dreaming of but if you hope for more than one as we did than expect that in order to start another IVF cycle you will have to have stopped breastfeeding 3 months prior. Sorry probably a bit far-fetched bit it came as quite a shock to me as we hoped for a small age gap but also hoped to breastfeed for quite a while so what to choose??

xx

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Saturday, July 5th 2014, 12:43pm

Oh forgot to add that the PGD cycle itself is very similar to a "normal" IVF cycle, as in:

1) woman receives some sort of hormonal stimulation (exact details would depend on the clinic's choice as best for the patient as there are several protocols to choose from)
2) eggs are harvested from woman and fertilised with man's sperms. Sperm has to be injected (ICSI) to make sure genetic material comes from the embryo and not some extra sperm stuck to the egg etc everything has to be quite controlled
3) Hopefully some eggs will fertilise (usually not all) and some of the fertilised embryos will start to grow (again likely not all)
4) Those that reach day 3 and around 8 cell big will be tested: one or two cells are taken out for testing
5) Embryos are let recover and to grow further and in the mean time the tests are done
6) Hopefully some embryos would have survived for day 5 and some of them are also normal so 1 or 2 can be tzransferred back into the woman

(We had 2 normal embryos at the end in each of our cycles although their quality varied, anyway 2 of those 6 proved to be great in the end as those are our daughters now)

Jess25

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  • "Jess25" started this thread

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Reg: Jun 29th 2014

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Saturday, July 5th 2014, 2:21pm

Thankyou for the info :) :) I guess I just have to be patient and realise this isn't going to be a quick process, I think that's what I need to get my head around as it's all very overwhelming even at this stage when the process hasn't even started yet!
Jess xx

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