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melf

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  • "melf" started this thread

Posts: 116

Reg: Jun 3rd 2008

Location: cleveland

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1

Friday, March 6th 2009, 5:00pm

implantation issues???

Hi Guys
been suggested I post this here as well as ivf link

We have just had BFN from 2nd treatment -just looking for some info

1st IVF- 5 eggs, 4 fert, 2 good grades transferred- bfn

2ND IVF- 9 eggs- consultantant decided to do half ICSI half IVF despite no sperm issues. All IVF failed, all ICSI fine. 2 excellent grades -3A and 6A transferred -bfn

We are wondering if perhaps have implantation issues?? Our hospital does not do any follow up tests (NHS- but grateful we have had opportunity for NHS treatment!)

Just wondered if anyone had any information on implantation issues or had any alternative treatment.
The pre ec scan showed a good lining

We are due for a review with consultant in a few weeks and just wanted to be prepared with as many questions and info as possible to see what we can do for our next try

Any help gratefully appreciated
xx
:thanx:
Melxx
Me and DH-35
TTC- since Nov 05
3 x IVF 08/09 BFNs
4th IVF/ICSI feb 10 private-BFP :weehee:

bab10 our precious bundle -Olivia arrived 22/11/10 bab10

Posts: 1,174

Reg: Dec 1st 2008

Location: UK

Children: (6 angels in heaven) 2 girls a previous relationship, and now a baby boy thanks to treatment

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2

Saturday, March 7th 2009, 7:26pm

Hi Melf

I tried to post here yesterday, but it didn't work?

It is possible that implantation issues can be the result of immune issues. Unfortunately immune testing can be expensive, so you may wish to eliminate any other causes if there is any?

I had my immune tested at the ARGC in London and it cost me £780 for the tests (they get sent to chicago ) and £150 consultation. and they don't test for everything. There are other consultants who will test and it is possible to arrange to have your blood taken and send them to Chicago yourself, using Fedex to ship them.

You can find a consultants who will test in this thread:
Collaborating Doctors???

This link is very good, as it is an Informational Test to Determine Need for Possible Immunological Testing
https://www.repro-med.net/tests/stest.php

and then if it suggests that you could need testing, it also tells you what therapy you may require

good luck

Lou x
Need reproductive immunology success stories please 2 help others :)

have u got immune issues?

melf

Ace

  • "melf" started this thread

Posts: 116

Reg: Jun 3rd 2008

Location: cleveland

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3

Saturday, March 7th 2009, 7:47pm

Thats great- thanks for the reply and links lou I will check those out. :thanx:

Its just so frustrating isn't it when no-one can seem to give you any answers as to why cycles fail etc :sadface:

Mel x
Melxx
Me and DH-35
TTC- since Nov 05
3 x IVF 08/09 BFNs
4th IVF/ICSI feb 10 private-BFP :weehee:

bab10 our precious bundle -Olivia arrived 22/11/10 bab10

Posts: 1,174

Reg: Dec 1st 2008

Location: UK

Children: (6 angels in heaven) 2 girls a previous relationship, and now a baby boy thanks to treatment

  • Send private message

4

Saturday, March 7th 2009, 7:55pm

Hi Mel

no problem, yes it is frustrating

hope you find your answers soon x
Need reproductive immunology success stories please 2 help others :)

have u got immune issues?

melf

Ace

  • "melf" started this thread

Posts: 116

Reg: Jun 3rd 2008

Location: cleveland

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5

Saturday, March 7th 2009, 7:58pm

Hi Lou

I did the immunological test and our score was 2 as we have never had a BFP/loss but it gives me more information when we see the consultant. I have ordered Dr Beer s book too!

We may be very fortunate in that we may have funding for a 3rd IVF on the NHS but we would happily pay for tests if available. Unfortunately I think our nearest centre would be Liverpool which is still quite a way but I will research further. We may have to have a weekend trip to london!!

Thanks again Lou
Take care
Mel x
Melxx
Me and DH-35
TTC- since Nov 05
3 x IVF 08/09 BFNs
4th IVF/ICSI feb 10 private-BFP :weehee:

bab10 our precious bundle -Olivia arrived 22/11/10 bab10

Posts: 1,174

Reg: Dec 1st 2008

Location: UK

Children: (6 angels in heaven) 2 girls a previous relationship, and now a baby boy thanks to treatment

  • Send private message

6

Sunday, March 8th 2009, 12:23pm

Hi Mel

I just redone the test and my risk assessment score is: 3!

What consultant are you going to see? an NHS consultant?

My GP sent my immune results to an NHS consultant, and the consultant sent a letter back saying he wasn't able to help me as the immune results are 'non evidence based'

I believe, unfortunately the NHS consider the immunolgy & fertility as "non-evidence based practise". this is because there hasn't been enough research using randomised studies using treatment & placebo drugs. I think.

I think this is because in a randomised study, some women would be given the 'real' fertility drugs, but half would get a placebo drug, and i think some women will not want to risk the placebo drug, because it may risk miscarriage. I think if you have immune issues, and misscarry, it reduces your chances, the more m/cs you have, the lower your chances, as effectively your body 'immunes' you against pregnancy.

I think this is the case? but I am not an expert.

I am not telling you this to worry you, as i know you haven't had m/cs, but just to forewarn you.

But maybe your consultant will be more open, and help you. I hope so.

Lou xxx
Need reproductive immunology success stories please 2 help others :)

have u got immune issues?

This post has been edited 1 times, last edit by "Louloulouisa" (Mar 8th 2009, 12:24pm)


deedee1

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Posts: 3,156

Reg: May 23rd 2008

Location: Cloud cuckooland

Children: 1 beautiful daughter

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7

Monday, March 16th 2009, 9:47pm

Hi Melf,

I've had 2 BFN's from 2 transfers from excellent quality blasts. My clinic are very progressive and recommended immune testing because of implantation failures. I'm relieved he did as an elevated NK count showed up.

As Lou said, these tests are expensive, but for me it was the right way to go as I could have wasted a lot more money and time going through treatments that had little chance of working. I had an inkling that something was up as I never get sick so it was easier for me to make the decision.

have a good chat with your consultant about your thoughts and concerns and see what he recommends.

Good luck!

melf

Ace

  • "melf" started this thread

Posts: 116

Reg: Jun 3rd 2008

Location: cleveland

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8

Tuesday, March 17th 2009, 12:47pm

Hi Deedee

Thanks for your message
I'm getting together a list of questions for our consultant appointment on the 9th april

Are you having any different treatment/meds since they found an elevated NK count???

Best of luck with your next FET hope it brings you a lovely BFP
xx
Melxx
Me and DH-35
TTC- since Nov 05
3 x IVF 08/09 BFNs
4th IVF/ICSI feb 10 private-BFP :weehee:

bab10 our precious bundle -Olivia arrived 22/11/10 bab10

deedee1

Newbie

Posts: 3,156

Reg: May 23rd 2008

Location: Cloud cuckooland

Children: 1 beautiful daughter

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9

Tuesday, March 17th 2009, 1:46pm

Hi Melf,

You name it, I'm putting it into every orifice in my body!!!!!!

I have 2 issues - a thin lining and now the killer cells. For lining, i'll be taking increased dosages of oestrogen, both through a patch and tablets, viagra, trental, asperin and lots of vitamins. For immune issues, I'll be on steroids, heparin and an intravenous drug called IvIg. So there will be a lot different to my last one.

Best of luck you also! On Paddys Day, have a lucky shamrock


:goodluck:

deedee1

Newbie

Posts: 3,156

Reg: May 23rd 2008

Location: Cloud cuckooland

Children: 1 beautiful daughter

  • Send private message

10

Tuesday, March 17th 2009, 1:46pm

Hi Melf,

You name it, I'm putting it into every orifice in my body!!!!!!

I have 2 issues - a thin lining and now the killer cells. For lining, i'll be taking increased dosages of oestrogen, both through a patch and tablets, viagra, trental, asperin and lots of vitamins. For immune issues, I'll be on steroids, heparin and an intravenous drug called IvIg. So there will be a lot different to my last one.

Best of luck you also! On Paddys Day, have a lucky shamrock


:goodluck:




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