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  • "Eeyore" started this thread
  • United Kingdom

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Reg: Sep 27th 2005

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Saturday, March 8th 2008, 7:05am


The ONLY way to know if Clomid is working or not is through monitoring. This may include:

• A cycle day 3 scan (looking for cysts)
• A cycle day 11 scan determining development of follicles and uterine lining
• A progesterone check 7 days following ovulation to determine whether the levels are sufficient to support pregnancy
• A post coital test (PCT) in the event other tests indicate an LH surge, or to see if the Clomid is creating hostile cervical mucus (unless you’re undergoing intra-uterine insemination (IUI).

Routine ultrasounds (tracking scans) aren't always offered to women on Clomid, but the LEAST you should expect a progesterone check (blood draw) around cycle day 21. The idea is that Clomid should have induced the production of progesterone, improving the lining of the uterus and/or stretching out the luteal phase of the cycle. Then...FIGHT for ultrasound tracking.

Follicular tracking is used to avoid over stimulation as well as to pinpoint ovulation. It is essetial for both the fertility team and you to have a greater understanding of your ovulatory pattern. Follicular tracking is normally performed by vaginal ultra sound scans from Day 9 of the menstrual cycle (Day 1 being the first day of bleeding). The scan will enable the follicle (fluid filled sacs which can contain an egg) in the ovary to be measured. When the follicles measure a certain size it can then be estimated when ovulation is likely to occur.

The main risk associated with Clomid use is the potential for developing Ovarian Hyperstimulation Syndrome (OHSS). OHSS can occur with the use of any type of ovulation stimulating drug. It happens when cysts begin to form on the ovaries, causing them to swell to a very large size. Typically, OHSS disappears without treatment but, without proper monitoring, the syndrome can become dangerous.

It is ESSENTIAL that your fertility specialist monitor you for signs of OHSS while you are taking Clomid. Potential complications include:

• kidney problems
• liver problems
• fluid collection in the lungs and stomach
• twisting of the ovaries

If the dose of Clomid has caused over stimulation, which can happen very quickly and can be dangerous, you will be advised not to have sex as the amount of follicles you have and the size they are at can't be controlled and to avoid a dangerous multiple pregnancy you are strongly advised to abstain.

Tracking scans is the most frequently discussed subject in the Clomid section! The bottom line is, INSIST on them so you maximise your chances of getting pg and safeguard yourself against the thread of OHSS - what is the point of just having a blood test after ovulation when it's too late?

They are available on NHS and privately, but it seems it some areas you have to ask (or insist!) on them. If Clomid is rescribed by a GP rather than a consultant, it's a struggle to get scans..but Clomid really shouldn't be taken without any aftercare, GP's may do bloods but they only tell you AFTER you have ovulated.

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My journey has now ended. 6 babies in Heaven.

'It'll be all right in the end - if it isn't all right yet then it isn't the end!'

Posts: 9

Reg: Jun 14th 2009

Location: Cardiff

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Tuesday, November 10th 2009, 9:12pm


Had an interesting chat with a chap from the HFEA. THey are quite apalled that lots of centres are advocating Clomid without follicle tracking as per NICE guidelines which means a higher chance of high order multiple pregnancies which is NOT good news. Is anyone prepared to let me know if they have had un-monitored CLOMID as I need to drop a line to HFEA and am not sure how widespread the problem is.

Bryan Beattie MD FRCOG
Consultant in Fetal Medicine
Dr R B Beattie MD FRCOG
Consultant in Fetal Medicine

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