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  • "starlight" started this thread

Posts: 274

Reg: Oct 3rd 2005

Location: middlesbrough

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1

Friday, July 6th 2007, 6:33pm

** POOR RESPONSE CHAT **

hi ladies

i remember a while ago reading a thread where one of the ladies was having trouble responding to stimms i cant remember who it was could someone please help me, i really would like to find the thread

many thanks zoexxxxx
me 31 dh 30
me severe pcos
iui dd born 25weeks gestation
6 failed stimmed iui cycles since may 2007





Posts: 2,235

Reg: Feb 11th 2007

Location: Cornwall

Children: My children are wonderful!

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2

Friday, July 6th 2007, 8:09pm

how do you mean, like not getting any/many follies or eggs?


Me 39, DH 40 Children, Lucy and DS (7)
Lucy lost in car accident 8th April 2002
TTC 6 years - ICSI x 4 - :BFN: x 4







Spider's Diary


Posts: 3,006

Reg: Oct 4th 2005

Location: Scotland

Children: Max born March 07 - thanks to frozen embryo transfer, our little miracle

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3

Friday, July 6th 2007, 8:13pm

You ok Zoe??


5 x ICSI b.f.n
1 x FET resulting in my gorgeous son born 2007

Posts: 2,235

Reg: Feb 11th 2007

Location: Cornwall

Children: My children are wonderful!

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4

Friday, July 6th 2007, 8:32pm

I didn't respond very well, last time ended up with 3 eggs but only 1 went in.


Me 39, DH 40 Children, Lucy and DS (7)
Lucy lost in car accident 8th April 2002
TTC 6 years - ICSI x 4 - :BFN: x 4







Spider's Diary


  • "starlight" started this thread

Posts: 274

Reg: Oct 3rd 2005

Location: middlesbrough

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5

Friday, July 6th 2007, 8:46pm

hi thanks

exactly spider no follies after 7 days of stimms

had a nightmare

Went to see nurse after scan she had phoned in sick so saw another nurse who i had problems with before not knowing what she was doing

she said right stop clomid!!!!!! im on menopur call back on next af i dont have af im dr at the mo

she looked in my notes oh your on 225measure of menopur i said no 75 she didnt believe me asked to see my drug sheet sure enough 75, she then proceeded to say i dont know what to suggest so i told her what the cons had said regarding dr so doses could be upped and lowered till will get right amount whilst my own hormones are suppressed , i told her he wanted me scanned every other day because of very severe pcos ovarian drilling done in nov etc. She then said we cant up drugs on first cycle this is not my first cycle she cancelled the last on !!!!!! she then went and got me 6 amps of menopur i dont know where from and told me to inject 150 today sat and sun and rescan on mon then see cons, to which she added my cons is on leave for 10weeks!!!!!!!!!!!!!! so i will be seeing another doc who is a lovely lady but does not speak english i need the whole consultation translated with me and nurse reading through notes to see if we can decipher them the last time i saw her she started me on stimms without checking bloods my cons couldnt understand why and i did not respond then the prescription she wrote out took 4 days to get as pharmacy couldnt read her writing nurses couldnt read notes and had no idea what i had been prescribed and couldnt get in tough with her. Nurse went to see my cons in surgery explained and asked him to write out a script after that i asked to see my cons so have not seen the doc i am seeing on mon since

i feel like it is all over i dont know what to do

thanks for listening love zoexxxx.
me 31 dh 30
me severe pcos
iui dd born 25weeks gestation
6 failed stimmed iui cycles since may 2007





  • "starlight" started this thread

Posts: 274

Reg: Oct 3rd 2005

Location: middlesbrough

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6

Friday, July 6th 2007, 8:47pm

hi spider

im having iui so need a max of 3 eggs cant even get 1!!!!!

protocol the same up till trigger shot and ec

take care love zoexxxx
me 31 dh 30
me severe pcos
iui dd born 25weeks gestation
6 failed stimmed iui cycles since may 2007





  • "starlight" started this thread

Posts: 274

Reg: Oct 3rd 2005

Location: middlesbrough

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7

Friday, July 6th 2007, 8:51pm

a while ago i was reading a thread and one of the ladies had no response on her first or second scan i cant remember who it was at all and am desperate to find the post

take care
zoexxxx
me 31 dh 30
me severe pcos
iui dd born 25weeks gestation
6 failed stimmed iui cycles since may 2007





Posts: 288

Reg: Apr 15th 2006

Location: South Wales

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8

Friday, July 6th 2007, 9:10pm

How long have you been stimming for starlight? I hope that you get some good news soon though


me 26
Got blocked tubes and cysts
icsi march 07 :BFN:
ICSI(assisted hatchng) in june :BFP:
Harley Joseph born April 2008

  • "starlight" started this thread

Posts: 274

Reg: Oct 3rd 2005

Location: middlesbrough

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9

Friday, July 6th 2007, 9:13pm

hi babygirl

7 days so by scan 10 days do you have any idea how long they let you stimm for my lining is 7.7mm today
love zoexxx
me 31 dh 30
me severe pcos
iui dd born 25weeks gestation
6 failed stimmed iui cycles since may 2007





Posts: 288

Reg: Apr 15th 2006

Location: South Wales

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10

Friday, July 6th 2007, 9:16pm

Hiya Zoe

I dont know how long they let you stim for but I do know that your lining has to be a certain way, I had a scan today and I have just finished my af so my lining was thin, and then they have said that I can start stimming today, have you got any follies starting to grow at all?


me 26
Got blocked tubes and cysts
icsi march 07 :BFN:
ICSI(assisted hatchng) in june :BFP:
Harley Joseph born April 2008

  • "starlight" started this thread

Posts: 274

Reg: Oct 3rd 2005

Location: middlesbrough

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11

Friday, July 6th 2007, 9:48pm

hi

no not at all loads of multiple cycst from pcos largest 5mm

i have been given 6 weeks worth of synarel dr so am on week 3 now

my lining was 6mm on baseline scan which was ok for starting stimms last thurs
i finished af on the tuesday,

i just wish my body would work i am so fed up

take care love zoexx
me 31 dh 30
me severe pcos
iui dd born 25weeks gestation
6 failed stimmed iui cycles since may 2007




This post has been edited 1 times, last edit by "starlight" (Jul 6th 2007, 9:49pm)


Posts: 2,291

Reg: Sep 27th 2005

Location: UK

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12

Friday, July 6th 2007, 9:57pm

Starlight - sorry your situation sounds so stressful. ?( I'm sorry I don't know what to suggest, but you must get to speak to someone at your clinic that you have confidence in. If you're having private treatment, you must feel that you're getting what you're paying for.

My clinic told me that they like the lining to be between 8mm and 14mm, but would proceed even if the lining is 7.8 or 7.9mm if everything else was looking perfect and if the lining was of very good quality.

Sorry you're fed up - hope your body starts responding this weekend. 8)

Posts: 288

Reg: Apr 15th 2006

Location: South Wales

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13

Saturday, July 7th 2007, 9:39am

I hope that everything goes ok for you starlight, like limpet says it must be so stressful for you at the moment and ask your clinic and they should give you some advise. goodluck hunni.


me 26
Got blocked tubes and cysts
icsi march 07 :BFN:
ICSI(assisted hatchng) in june :BFP:
Harley Joseph born April 2008

Posts: 2,235

Reg: Feb 11th 2007

Location: Cornwall

Children: My children are wonderful!

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14

Saturday, July 7th 2007, 6:19pm

I always had to go a couple of days longer stimming than planned for and was on the top drugs last time 225 am and 225 pm, it was puregon for ICSI. I only got one scan, I think 10 days in, always on a Friday and then would not go in until midweek for EC.

Sorry your news is so pants, Starlight, but it must be made worse by not feeling confident about your nurse. I had one who had me in tears but her advice was totally contradicted by the main nurse who luckily I saw on the same day. We had to decide whether or not to go ahead with only 3 follies, you need more for ICSI really.


Me 39, DH 40 Children, Lucy and DS (7)
Lucy lost in car accident 8th April 2002
TTC 6 years - ICSI x 4 - :BFN: x 4







Spider's Diary


Posts: 242

Reg: Mar 6th 2007

Location: Leeds

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15

Tuesday, October 16th 2007, 2:30pm

Anyone else in the same situation - no response

Hi,
I had an IVF cycle abandoned in August as I didn't respond to the max dose of Menopur. I was told in April that I was having an early menopause (FSH level was 15.9) . Our consultant told us that if I didn't respond to the max dose of drugs then I wouldn't respone on subsequent tries. Whilst I know that she knows what she's talking about I just keep wondering "what if" and if by any miracle I would respond differently if we had another go ........

I was just wondering if anyone else has been in this situation with a positive outcome or whether I really so let go and concentrate on alternatives 100% of the time rather than 75% of that time that I have been.

Thanks
Annette
ME 42 DH 42
H'copy Nov 05
2 Early m/c 06
March 07 Early m'pause.Ovaries inactive
IVF Aug 07 No response to drugs Adoption only optn
MIRACLE BFP Oct 08 !!



fairy

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Posts: 5,503

Reg: Oct 16th 2006

Location: depend's which room my twins have decided to vanish to!

Children: We have two VERY precious miracles! Twin girl/boy!

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16

Tuesday, October 16th 2007, 3:41pm

Hiya Hun!

Sorry, I don't come with good news to share with you, or any experience to share with you, but I wanted to come on and wish you loads of luck with which ever you decide to do, you will know whats best for you in the long run.

:goodluck: with everything Netty xfingers

Take care x


Me 30, DF 36
Ella-Louise and Ayden were born 24th December 2008 (11 weeks early) - Our family is now complete ... So we thought! A new bundle is on it's way! EDD 27th August 2012!


Abbie

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Posts: 87

Reg: Nov 15th 2006

Location: Herts

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17

Tuesday, October 16th 2007, 3:48pm

HI

Cannot really offer you any advice just loads of luck.

My first cycle I had 19 follicles, 13 high grade eggs.

This cycle I had different drugs, 14 follicles but only 7 high grade eggs so medication does made a difference
________________________


Me 39 DP 41
Male Factor
First ICSI March 07 :BFP: then :BFN: (biochemical)
Fibroid removed June 07
2nd ICSI Oct 07 Assisted Hatching OMG :BFP:



This post has been edited 1 times, last edit by "Abbie" (Oct 16th 2007, 3:49pm)


mrs_smiff

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Location: Somerset

Children: 5 kids aged 21,18,14,13 and a little miracle born April 09

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18

Tuesday, October 16th 2007, 4:09pm

I would seek a 2nd opinion if I were in your position to be honest. The fact that you conceived only last year says that there must be some hope still. (I can't imagine your fertility just disappearing overnight). Is there any way you can book a consultation with another clinic to be sure that everything has been covered?
Me 35,DH 36 (Severe Oligospermia.).
4th ICSI :BFP:
I have 4 lovely big kids
Thomas Derren (Thom) July 1990
Luke Benjamin August 1993
Harley John Oliver June 1997
Alexandria Aimee Jay (Alex) July 1998
Lochlan Cassius James April 2009 (4th attempt at ICSI)



Posts: 242

Reg: Mar 6th 2007

Location: Leeds

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19

Tuesday, October 16th 2007, 4:17pm

Thanks for your replies guys.

I think getting a second opinion is a good idea.

Will I be able to have my notes transferred from one hospital to another in the same city ? Been having treatment at St James in Leeds but the LGI also does assisted conception even though they are part of the Leeds Reproductive Medicine team.

Thanks again, will discuss with DH tonight, think it will make him happy to give it another go even if it's only a 1% chance of success !

Annette
ME 42 DH 42
H'copy Nov 05
2 Early m/c 06
March 07 Early m'pause.Ovaries inactive
IVF Aug 07 No response to drugs Adoption only optn
MIRACLE BFP Oct 08 !!



Posts: 2,037

Reg: Jul 19th 2007

Location: cumbria

Children: 1 lovely Step Son aged 17

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20

Tuesday, October 16th 2007, 4:22pm

:hi: Netty :goodluck: with everything :xxx3:

ME 32
DH 38
TTC 4.5yrs
Lap & Dye 07 very mild endo
6 clomid cycle's 100mg all :BFN:

Posts: 242

Reg: Mar 6th 2007

Location: Leeds

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21

Tuesday, October 16th 2007, 4:25pm

I do have other signs of an early menopause as my cycle varies from 20 to 33 days, I think I went 14 days a few months ago as well !! I have real trouble sleeping, go to the loo alot.

Ahhhhhhhh

Just stuggling to decide what to do and I have two big fibroids which may need removing (at a cost of course !). Think I'll start making a note of my questions.

The big question is whether to ask my current consultant or go elsewhere.

Annette
ME 42 DH 42
H'copy Nov 05
2 Early m/c 06
March 07 Early m'pause.Ovaries inactive
IVF Aug 07 No response to drugs Adoption only optn
MIRACLE BFP Oct 08 !!



mrs_smiff

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Posts: 5,387

Reg: Jan 10th 2007

Location: Somerset

Children: 5 kids aged 21,18,14,13 and a little miracle born April 09

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22

Tuesday, October 16th 2007, 5:09pm

There shouldn't be any problem with getting your notes to another clinic hun. You are entitled to a copy of them at any rate, so you could get a copy yourself, and take them to another consultant. I guess if they could categorically tell you that there is no chance for you with IVF, then you will be able to move on and seek alternative solutions. It's the not knowing for definate that causes all the angst, or having doubts. I hope you get the answers you so desperately need hun.
Me 35,DH 36 (Severe Oligospermia.).
4th ICSI :BFP:
I have 4 lovely big kids
Thomas Derren (Thom) July 1990
Luke Benjamin August 1993
Harley John Oliver June 1997
Alexandria Aimee Jay (Alex) July 1998
Lochlan Cassius James April 2009 (4th attempt at ICSI)



Posts: 769

Reg: Dec 30th 2007

Location: South London

Children: Was Lister

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23

Tuesday, March 4th 2008, 8:59pm

Consultant feedback - poor responder

We've just come back from our follow-up meeting with our consultant and it was quite depressing.

In a nutshell he says I'm a poor responder (6-7 eggs at EC but 50% fertilisation rate) and that we would be advised to stop ICSI using my eggs after 3-4 attempts (we've 2 under our belt).

Has anyone else been told this type of information and how did they take the advice? Did you carry on past 4 attempts or did you opt for egg donation as our consultant has advised?

If we stay with the same clinic he's suggested a hyscoposcopy to see if there's any endo in me (even though I don't suffer any of the symptoms and he found no evidence during the EC) as there's a piece of research from the US showing that 29 women who didn't know they had endo had this treatment and 15 of them went on to conceive.

To be honest this wasn't the type of conversation I expected to be having after just 2 ICSI attempts as I thought we'd have more chances - so feel quite stunned.

Dissapointed pickles




4 ICSI - all BFN
Poor responder (6 eggs max on left ovary only)
High NK cells
Considering Egg Donation

kar1

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24

Tuesday, March 4th 2008, 9:18pm

aww hun

im sorry it didn't go well and i think that he was wrong to talk of donar eggs this some considering you got 50% fertilised

ok you didn't make great eggs but to talk of donar eggs just yet was uncalled for

what were your embryos like?
TTC 12 years

2 early losses

lots of ops and tx

both tubes removed

5th fresh short protocol
:BFP:

Tyler May born 5/5/2010 by emergency c section. Tyler is our sunshine

roxy

Ace

Posts: 317

Reg: Feb 5th 2008

Location: Wales

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25

Tuesday, March 4th 2008, 9:38pm

im so sorry hun, if you dont mind could i ask you some questions i have got severe endometriosis and had an op about 15 months ago to remove adhesions, i was due to have another one before my ivf but they decided to go ahead and try anyway. i had 9 eggs retrieved but only 3 fertilised, i was told that this was 'below expectations', im wondering now after reading your thread if my dreaded endo played a part. How did he say the endo was affecting your eggs? i was always told that endo caused blockages to tubes but never anything about egg quality?

roxy

Ace

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Location: Wales

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26

Tuesday, March 4th 2008, 9:43pm

P.S I just thought of something my consultant (endo specialist) told me after each laser removal operation (ive had 7) that as long as they laser the endo away, and there is no blockages tubes etc conceiving should not be a problem x x

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Children: One due in Jan, 10.

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27

Tuesday, March 4th 2008, 10:49pm

RE: Consultant feedback - poor responder

Sorry to hear follow-up was disappointing. I got similar news from my last con. She said endo affects egg quality ie why poor eggs and low grade embies. And she talked about egg donor and stuff. I changed clinic, solely based on the result percentage. But my new consultant said that even though I have endo it should cause such a problem. I am on my 2ww now so only time will tell.
Getting a hysteroscopy to get it all checked out may not be bad idea. But will it be under NHS.
Were you having ICSI cause of male factor? If yes did he mention it being a cause of low fertilisation.

Posts: 769

Reg: Dec 30th 2007

Location: South London

Children: Was Lister

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28

Wednesday, March 5th 2008, 6:58am

Thank you all for comments

Kara - embryos all good quality (cell 5 and 4 on day 2 transfer and all fine told by embryologist. First set were grade 6/4 on day 3 transfer all fine) I felt he was very pessimistic but then he is the expect. Didn't sleep well last night :(

Roxy - I'll try to remember the name of the research and hunt it down on the website for you. He talked about endo affecting implantation so not eggs directly.

Rightuns - we wre thinking of changing clinics and this has just confirmed it for me as I think we need to experience another consultant. I don't necessarily disagree with him but I just want to see if another routine/drugs will influence my body and if I don't try now I'll only regret it. I don't think I have endo as I've never had any symptoms (best friend has it so I know what to expect) but I will do this operation if it rules out endo or other causes. Will try NHS first but depending on timing may have to go private.

We are on ICSI for male factor - poor sperm.

Pickles




4 ICSI - all BFN
Poor responder (6 eggs max on left ovary only)
High NK cells
Considering Egg Donation

Posts: 1,363

Reg: Feb 16th 2008

Location: Surrey

Children: TTC child no 1 hoping for BFP 08

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29

Wednesday, March 5th 2008, 12:23pm

:hi: Pickles,


sorry you have had such such a rough time, my xfingers are crossed for you and :goodluck: will TX.

Im sorry I can't offer any advice but I have not started any TX yet but didn't want to read and run. Take care.


:xxx3:

dwarf

Star

Posts: 1,283

Reg: Oct 4th 2005

Location: in my own world

Children: ds 2yrs

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30

Wednesday, March 5th 2008, 1:03pm

Different scenario, but we chaned clinics and think sometimes fresh set of eyes and ideas sometime boosts pma as well as changing result. I don't regret it although was nervous at the time wondering if we did the right thing. Dh used to say change is as good as a rest. Even though new cons echoed some of what old one said, found out a lot more too. Good luck.
Me pcos. Ds born nov 2005 - 1 round clomid.
TTC no2 since April 06.
6 rounds clomid (skinny womb lining + vaired response),
3XIUI, 1X IVF.
BFP 29/12. All fingers and toes crossed.



chatterbox

Megastar

Posts: 8,584

Reg: Nov 30th 2007

Children: Two heaven sent miracles!

Thanks: 36 / 16

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31

Wednesday, March 5th 2008, 4:41pm

Can I ask a question folks.... ?(

In my first round of IVF last Oct/nov, which was 3 months after major abdo surgery in Aug I had a fair response on my right ovary and poor if any on my left. the nurse said this sometimes happens.
Of the 10 follicles that appeared on my right, only 4 eggs were retrieved and 3 of these fertilised. 2 were transferred, 3rd didn't do its thing.

Noone said I was a poor responder, but comparing myelf to the results and comments above, it would seem I am... would it be due to the surgery so close to treatment? (I had to move quickly though).

Would you say this was a poor response, should it be somehting i'm asking at my next check up (its on Mon, so this thread very helpful).

I'd really appreciate any thoughts!

:xxx3:

Me 40 DH 35 TTC 10yr
peritoneal mesothelioma, cystectomy 97 & 00
peritonectomy, lost both tubes & most of left ovary Aug 07


Dec 07 BFP b/ov m/c 9.6wk
July 08 BFN
Dec 08 BFP b/ov m/c 9.6wk

July 09 BFN
Nov 09 BFP 2 x sacs 1 b/o 1 no hrtbt m/c 9.2wk
May10 BFP at 8+4 m/mc @10wk scan ERPC

Found: High NK cells, DQ Alpha match, LAD neg & PAI-1 pos...

NOV 2010 - Immune IVF at CARE Manchester
:BFP: [zx076] :girl: born 25/8/11

OCT 2012 - Immune IVF at CARE Manchester
:BFP: [zx076] :boy: born 24/6/13

kar1

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Posts: 12,830

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32

Wednesday, March 5th 2008, 5:19pm

pickles any news on hope long the wait for the op is?

chatterbox some clinic say less than 6 eggs in poor responce other say less.

remember girls each cycle is different, it really it, mine have been

pickles i really don't blame you for changing more clinic your con doesn't sound great.

each of my cycles something has been changed, whether it be more drugs or added drugs.
TTC 12 years

2 early losses

lots of ops and tx

both tubes removed

5th fresh short protocol
:BFP:

Tyler May born 5/5/2010 by emergency c section. Tyler is our sunshine

Posts: 769

Reg: Dec 30th 2007

Location: South London

Children: Was Lister

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33

Wednesday, March 5th 2008, 8:34pm

I only seem to have one ovary functioning so that has added to my problems - right produces on average 5 and left ony two. If it was normal then maybe things would be different.

The nurse tried to contact me today but I was in a meeting and couldn't call back. I assume I can have the hyscoposcopy at the clinic we're still with and then move to the new one after this. Although, we have an appointment at a new London centre on March 26 so not sure about timings.

Still can't find that research the consultant was talking about.

P




4 ICSI - all BFN
Poor responder (6 eggs max on left ovary only)
High NK cells
Considering Egg Donation

ZIG

Ace

Posts: 346

Reg: Oct 4th 2005

Location: Cumbria

Children: Isabella Mae (ICSI No.3) and Ruby Olivia (natural)

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34

Wednesday, March 5th 2008, 9:42pm

Hi there

It sounds like you have got to the point I got to 4 years ago. My dh also had low sperm quality and quantity and I was a "poor responder". After 2 ICSI cycles at Leeds using both regular and short protocols (I had no down regging and then high stimming for my 2nd tx - both cycles produced limited follicles and eggs, which then only resulted in 1 or 2 fertilising and dividing) my cons started to talk about egg donation. I was mortified, but after looking at a waiting list of possibly 3 or 4 years for a donor in the UK, we tried tx in Cape Town as there were plenty of donors and the clinic had a great reputation. It was unsuccessful, even with 3 eggs implanted.

So back to Leeds where the cons reluctantly suggested a lap and dye. Whilst "in there" she found I had endometriosis which she zapped, and she commented that my ovaries looked small which indicated that my reserve was running out. But the good news (!) was that my tubes weren't as blocked as she had first thought.

So, what next? I really disliked my cons and had begun to dread the 3 hour trek to the clinic, so time for a change. I just KNEW that it would work for me one day, don't ask me how, but I did, so I wasn't prepared to give up just yet. I asked my fab FZ mates to recommend a clinic closer to home, and they suggested Gateshead. So off I went for a visit, clutching the gory pics and results from my lap and dye op, along with my notes from all of the previous tx's. The new cons at Gateshead was so lovely and positive I could have hugged him - infact I did! He recommended another ICSI IVF attempt with a shortened protocol (reduced down regging and then high stimming). He warned me that I would only produce , a few follicles and eggs, but felt that the quality could be good enough using this regime. We immediately went on a serious health kick, lost weight, adopted a strict anti-thrush diet and had regular acupuncture and bowen. We both felt healthier and less stressed. My dh's sperm count and quality even improved.

To cut a v long story short, my tx was successful after producing only 5 eggs, only 3 of which went on to fertilise and only 2 divided. Baby No. 1 arrived Dec 05. Then last year we found out I was pg NATURALLY. So we now have two daughters who are 5 months old and two years old.

Good things do happen. Gosh, I've been saying that a lot lately on this site! Take control, think and act positively, look after yourselves and believe. Make changes if you have to, and put everything into getting healthy and less stressed (easy to say!).

Good luck. Sorry this was such a long drivel!

Hugs
Zig x
Me 38, DH 44. 2002-2004 2x ICSI's, 1x egg donation. Changed clinics for own eggs ICSI/tx no.4 - BFP 27/4/05! Mummy to Isabella after early c-section 15/12/05, due to LLP. Baby No.2 (huge 'natural' surprise!) Ruby Olivia arrived 29/09/07 via emergency c-section.

Posts: 3,072

Reg: Dec 18th 2007

Location: Bath

Children: one perfect little miracle baby boy - now trying for a little brother or sister !!

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35

Wednesday, March 5th 2008, 9:51pm

Hey Pickles can't answer your question Hun but just wanted to say hi and that i'm thinking of you, hope you get things sorted and find the answers you need blowkiss


IVF 5th time lucky
- BFP
Trying for No 2 - BFP


Posts: 2,005

Reg: Aug 28th 2007

Location: Dream Castles

Children: One due in Jan, 10.

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36

Wednesday, March 5th 2008, 9:53pm

Feel so positive after reading your post, Zig. Thanks. clap

Katy

Ace

Posts: 958

Reg: Jun 7th 2007

Location: Manchester

Children: 1 daughter!

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37

Thursday, March 6th 2008, 10:19am

Hi Pickles,

I'm also a poor responder (can't even get to egg collection it's so bad!) I only ever produce one or two follicles.

My consultant has also told me I should go for egg donation . I don't think though that they fully appreciate that egg donation is a huge step emotionally and just look at it as, well you just want a baby right? !!

I don't think you should even consider giving up on the ICSI just yet and I agree with Zig in that you should look for a better consultant and also go on the health kick. I've started a healthy eating regime and have been doing it for the last month or so (and have lost half a stone in the process!). I'm also doing acupuncture once a week and seeing a nutrionist. I look at it as giving it all before I can go onto egg donation. At least then I can say I've tried.

I'm very interested about any link there may be between endo and egg quality. If you find any more out about that I'd be really interested to hear.

I'm also having a blood test in a couple of weeks to test my Anti Mullerian hormone which is supposed to tell you how good your egg reserves are.

This news hit me like a ton of bricks so I know how you feel, but reading Zigs post has given me a bit of hope, so I hope you can take something from it as well.

Best of luck
xxx



1st IVF Oct 07 convert to IUI due to poor response to drugs Bfn
2nd IVF Feb 08 poor response convert IUI Bfn
29.03.08 - Natural Bfp - early loss
Aug 08 3rd ivf BFP!!!
One gorgeous daughter!!!
Trying to recover from Post Natal Depression
Jan 10 Natural Bfp!!! :8o:

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Friday, March 7th 2008, 8:55pm

Ahh Zigs that really is a heart warming story and makes me feel more positive that goods things do come to those who wait. I was also interested to learn how your cons changed your routine as a poor responder - I'll take this learning with me.

Thanks Sammysue for your thoughts. How's things with you?

Hi Katy thanks for your message. Now the shock has passed I'm more p***ed off with consultant for giving up so soon. It's not that I'm ruling out on egg donation in the future but surely it's yet the time to consider.

I'm going to have my bloods taken again and I'm going back to my doctor to see if he'll refer me for hysteroscopy so we can see what's going on up there. We're also going to visit a new clinic at the end of the Month.

I really want to give accupuncture a go to see if it makes me feel better and might have an impact on other tx. I've really got to get on that health regime as well. I'm going to the gym about twice a week but I know it's not enough. I'm going to go to weightwatchers on Tuesday as the start of the journey.

I'm still hunting for that research he talked about......leave it with me.

Tell me more about this Anti Mullerian hormone - what's that all about?




4 ICSI - all BFN
Poor responder (6 eggs max on left ovary only)
High NK cells
Considering Egg Donation

Paris

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Sunday, March 9th 2008, 2:35pm

hi pickles, i too am a poor responder, i have a low egg reserve. started trying five years ago, and we had just started our 9th cycle, i found out last week that i had fallen pregnant naturally, we were truly amazed as had accepted the fact we would need donor eggs, we had no expectation of this one working. so all i can say is please dont give up yet, if it can happen to us it can happen for you.
if you dont mind me asking what drugs are you taking and what qty? and have you thought about acupucture, i am convinced this is what did it for us.
take care; x
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Sunday, March 9th 2008, 6:41pm

Hi Paris

That's fantastic news on your BFP after what you've been through.

I really want to try accupuncture this time round but I'm not sure when is the best time to start. Do you start a couple of months before treatment or nearer to the treatment date?

The first time I was on Gonal F 225 and the second time I was on 375 but nothing changed. Do you think if I change drugs it might make a difference and I'm thinking that maybe a short rather long protocal might make a difference but don't know enough about that yet.

Off to tell DH about your good news...

P




4 ICSI - all BFN
Poor responder (6 eggs max on left ovary only)
High NK cells
Considering Egg Donation

Katy

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Sunday, March 9th 2008, 7:09pm

Hi Pickles,

The AMH test is to test what your ovarian reserve is like and to see if you have any eggs at all. It's supposed to be more accurate than looking at the fsh/lh levels.

Theres an article written by my cons on the Alexandra Hospital website (which is in cheshire). If you look under Dr Nardo you should see it there. He's done quite a bit of research on it. I don't know what difference it will make treatment wise, but I suppose it will give me an indication of just how many eggs I have there!

I'm so glad that there are some positive stories coming out about people with poor response, because until recently no one had really said much about it on this site that I could find. It gives me some hope.

As for acupuncture, it would be wise to try and start it a couple of months before if you can because apparently they can move any energy stagnation that is occuring in the body and prepare you for any treatment that you have. It's not exactly cheap but the way I see it is just factoring it in with the treatment we have.

I've been on the short protocol both times that I've had tx. I don't think it would make a great deal of difference as the long protocol just stops everything then restarts it. I think the long protocol is more for people who have irregular cycles?? But I could be wrong. I was also told by my cons that the amount of drugs that you have won't make any difference. I thought that if I was put on a higher dose it might make me respond more. The first tx I was on 300 and 225 of menopur every other day and I got two follicles on my left and none on my right. Second try I was on 450 of puregon for the first 3 days then they gradually reduced my dose to 375 then I think 300. I got two follicles on my left (one of which disappeared??!) and on on my right which was just too small, 13.5mm when it needed to be 15mm. So my theory was well, my right has responded this time so that's got to show that more of the drug has worked and if it was kept at the higher dose, it may just respond. But the cons said that it didn't matter and that I would always respond the same way. I'm dubious about that and will definately be discussing drug doseage more on my next go.

I'd definately like to hear about your progress though and see how you get on.

Good luck

(And congratulations Paris!!!!!!!)



1st IVF Oct 07 convert to IUI due to poor response to drugs Bfn
2nd IVF Feb 08 poor response convert IUI Bfn
29.03.08 - Natural Bfp - early loss
Aug 08 3rd ivf BFP!!!
One gorgeous daughter!!!
Trying to recover from Post Natal Depression
Jan 10 Natural Bfp!!! :8o:

Paris

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42

Monday, March 10th 2008, 9:13am

Hi

Because i am a poor responder my first 3 cycles were natural cycles whereby they only stimulate to collect 1 egg, don’t know if this treatment is common in the UK or not, so the first egg they retrieved did not fertilize, so the month after on day 20 of my cycle i started a drug called provammes (tablet x2 a day) once i got my period i started injecting, menupur i think, anyway, 2nd natural cycle they collected the egg it fertilized but BFN, 3rd natural cycle got into theater and the egg had already left, was totally gutted, the doctor that carried out the procedure then came to talk to me to find out why i was on a natural cycle and not a full stimulated, so explained i was a poor responder etc, anyway cut a long story short(er) he asked me to make an appointment to see him to try a full stimulated cycle, so had my first full stimulated cycle, 300 gonal f, did not respond properly (had 3 eggs) so had an IUI instead of an IVF, same happened to my on next two cycles, then started acupuncture, got 6 eggs, most i have ever had, 4 fertilized two put back in but BFN, next round i got 6 again but another BFN, this was our last attempt with our own eggs but got pregnant before started stimming, i am convinced its the acupuncture, that and drinking religiously 2 ltrs of water a day and not taking hot baths. If you can afford the acupuncture i would recommend it, ask your clinic if they know someone, and deffo try stat it before your treatment.
Good luck xxx
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dwarf

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43

Monday, March 10th 2008, 11:20am

Don't rule out reflexology either. For me worked really well
Me pcos. Ds born nov 2005 - 1 round clomid.
TTC no2 since April 06.
6 rounds clomid (skinny womb lining + vaired response),
3XIUI, 1X IVF.
BFP 29/12. All fingers and toes crossed.



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44

Monday, March 10th 2008, 6:38pm

Thanks everyone for the great advice.

Paris - really interested by your results after accu and Katy I went onto your consultants site to read up on how to measure the ovarium reserve - very useful.




4 ICSI - all BFN
Poor responder (6 eggs max on left ovary only)
High NK cells
Considering Egg Donation

This post has been edited 1 times, last edit by "Pickles" (Mar 10th 2008, 6:39pm)


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45

Thursday, March 27th 2008, 12:15am

Poor response to IVF

Hi
My 1st cycle of IVf was abandoned and they opted for IUI instead which has been unsuccessful - I am not surprised as the previous 3 treatments didn't work. The reason was that the left ovary didn't respond at all and there were only 3 follies on the other one of which only one was the right size. I was on buserelin to down reg and then menopur (300 dose then upped to 450 for the last couple of days). I have my follow up appointment at the beginning of May, and need to talk over the options, but does anyone have experience of this? I am also looking at the option of acupuncture which seems to have worked for a lot of people as well.
Common sense would suggest that they might be able to up the dose next time round, but I haven't found much info either way to suggest that this would work. i'd be really grateful for any input!
Thanks!

Sarah

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46

Thursday, March 27th 2008, 7:07am

Hi Sarah

I'm sorry your TX didn't go as planned! It is very frustrating and upsetting.

I only had 2 follies at my day 8 scan and decided not to go on with that cycle. I was distraught (but looking back now I think some of that was probably the drugs)

We had our follow up and our consultant is going to try a cetrotide cycle next time. Basically, just stimms and cetrotide from day 6 or so to stop ovulation occuring. I just feel more positive knowing we are going to try a diff approach this time.

Anyway good luck and f you have any questions PM me.

P x
2 gorgeous girls and 1 on the way

Duffymoon

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47

Thursday, March 27th 2008, 7:34am

RE: Poor response to IVF

Hi Sarah....there's a girl on here called Katy who's had two similar experiences to you.

She has a diary here Katy's Diary but I think you need to get to 25 posts before you can access the diary section.

Get posting!

Best of luck.

xxxxx


4 x ICSI BFN
5th time :BFP:
:boy: :girl:




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48

Thursday, March 27th 2008, 8:12am

RE: Poor response to IVF

Hi there

Not had a problem with poor response myself, but am sure Jane April had some of her medication changed this cycle due to previous poor response and she's just had her BFP, so maybe look at her diary / pm her???

Hope this helps, good luck

c
xx
Cathie

Proud mum to Eric after 3 years TCC!!!

Duffymoon

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Thursday, March 27th 2008, 8:19am

RE: Poor response to IVF

Quoted

Originally posted by Cathie
Hi there

Not had a problem with poor response myself, but am sure Jane April had some of her medication changed this cycle due to previous poor response and she's just had her BFP, so maybe look at her diary / pm her???

Hope this helps, good luck

c
xx


Hi Cathie....I'm pretty sure Jane's issue was quality of eggs not numbers and she did get to EC on the two times before this BFP so not sure it's directly related to Sarah's issue.

Like your thinking though!

xxxxx


4 x ICSI BFN
5th time :BFP:
:boy: :girl:




Pootle

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50

Thursday, March 27th 2008, 8:38am

Hi Sarah

Dizzyduck also had a similar experience and I think has had 2 cycles converted to IUI. Not sure where her diary is - maybe IVF/ICSI situation.

I was also classed as a poor responder - my left ovary didn't produce anything and only 3 follies on my right. My clinic went ahead with EC and ET though.

Wishing you lots of luck for your follow up and future treatment.

x






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