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  • "hellinida" started this thread

Posts: 7

Reg: Aug 13th 2009

Location: hellas

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Friday, August 14th 2009, 11:46am

Azoospermia and Sertoli-cell-only syndrome

In two months (April-May) my husband had 3 tests.All showed azoospermia.
After having done all the possible tests he had a TESE surgery and a testicular biopsy.
Our urologist said that during the TESE he found 2 sperms not moving and not in the condition of preserving them. In addition he saw minimum spermatogenesis.
He also told us that the sample he had taken and had sent it for istological examination showed Sertoli-cell-only syndrome.
He told us that the possibility to improve the situation is 5%. However, he suggested us trying the therapy with ormones.
Do we have any chance accomplishing anything with this therapy?
Is there something else to try?
We are devastated!

Posts: 2,505

Reg: May 2nd 2007

Children: A boy and a girl, both living in London

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Friday, August 14th 2009, 1:07pm

RE: Azoospermia and Sertoli-cell-only syndrome

Hi Hellinida,

Just to clarify what you have been told. Sertoli cells are the testicular cells that support the sperm producing cells, but do not in themselves make sperm. Sertoli-cell only syndrome is a very common reason for male infertility and sadly is untreatable as the sperm producing cells have never developed in utero. This is a very different situation from a hormone deficiency and is not likely to respond therefore to taking hormone treatment. I would put the chances of getting any adequate response to this at rather less than 5%, but you might still wish to try this for a limited time just to know that you have tried.

Kind regards,

Fertility Scientist and Andrologist
Fertility Counsellor, Holistic Therapist and Hypnotherapist
Providing Fertility Information, Assessment and Enhancement.
Natural family planning teacher.