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  • "Tigerlilly" started this thread

Posts: 118

Reg: Oct 26th 2008

Location: Oxford

Children: 1 beautiful girl from 1st IVF attempt

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Sunday, March 4th 2012, 8:49pm

Anyone had Metformin?

Hi everyone,

Been such a longtime since I have been on here but thinking about trying IVF again.

Ended up with OHSS last time with 22 eggs but ended up with a wonderful baby girl so all worth it!

The clinic has suggested I take metformin for 2 months before treatment but don't know anything about it.

Has anyone had metformin and for what reason?

Many thanks

TigerLilly x
TigerLilly xmas39

Posts: 1,498

Reg: Apr 14th 2009

Children: A son and daughter - our family is complete :)

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Absolutely love being a mum of 2 but OMG it is hard work and very tiring! Wouldn't change it for the world though :)

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Monday, March 5th 2012, 7:26am


I am a firm believer in Metformin. I had IVF in October 2009, which was a BFN. We then did FET about 6 months later and I had a chemical pregnancy. I also had a chemical pregnancy when I was taking Clomid a year before starting IVF. Anyway, we were about to start our 2nd attempt at FET and I asked about Metformin as I had been told it can help balance hormones as with PCOS (which I have) we have a hormonal imbalance, which can cause chemical pregnancies. Fortunately my consultant agreed and said it would do no harm for me to start it a couple of months before we did treatment. I was on 1000mg a day. As you can see from my ticker this FET was successful and I now have a beautiful son. I really do believe the Metformin helped me have a healthy pregnancy.

Good luck xx
An almost 4 year old son and a 21 month old daughter :)

Posts: 355

Reg: Sep 27th 2011

Location: Cumbria

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Monday, March 5th 2012, 7:35am

I was put on a high dose of metformin prior to strating my ICSI cycle due to having PCOS, I took this right through the cycle and we were very lucky that we got pregnant first time. I continued to take the metformin right up until 12 weeks of pregnacny and then come off it. It is not a nice drug to take as it can make you feel very sick but it is worth it for the benefits especially if you have PCOS. My consultant prescribed this for me privately which would have cost a fortune, I went to my GP and asked if they would prescribed it and they did which cut down the costs a little bit.
<a href=""><img src="" width="200" height="80" border="0" alt="Lilypie First Birthday tickers" /></a>

Lisa Lou


Posts: 1,560

Reg: Nov 1st 2008

Location: kent

Children: 2 gorgeous little Boys - our miracles!

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I have the most gorgeous boys on the planet! x

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Monday, March 5th 2012, 8:42am

I'm a number one fan of metformin, I've had two natural pregnancies which both resulted in miscarriage and my first attempt of Ivf gave us a BFP but this too unfortunately ended in miscarriage aswell. Before starting my 2nd round of Ivf I asked and pushed for metformin to be included in my cycle and the clinic agreed.. The cycle resulted in OHSS and all 17 of my embies were frozen but it was from one of these lovely embryos that I got my gorgeous son following a FET three months later.

I believe the drug helped me produce quality eggs.. Which meant I did not miscarry. My consultant agreed that women Pcos are at risk of more m/c due to poor egg quality caused by poor hormone balance.

So yes it is a very sickly drug but well worth it if your a woman with Pcos x

Lisa Lou

ME: 30, PCOS
DH: 32, Low Count

1st ICSI: BFP miscarriage @ 9 weeks
2 natural BFP both lost @ 8 weeks

March 11 FET: Beautiful BFP!! Baby Jayden arrived safe and sound on 29/12/2011, he is perfect!!
December 2012 shock natural BFP!! Baby Shay arrived quickly on 28/07/2013, he is gorgeous!!

  • "Tigerlilly" started this thread

Posts: 118

Reg: Oct 26th 2008

Location: Oxford

Children: 1 beautiful girl from 1st IVF attempt

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Sunday, March 11th 2012, 7:45pm

Thank you all for your replys.

Its a tricky one because my first IVF worked well although I have mild PCOS and did end up with OHSS but egg quality was very good.

Not sure whether to give it a go, I will have to have a think.

Lovely to hear about all of your success stories!

TigerLilly xmas39



Posts: 8,584

Reg: Nov 30th 2007

Children: Two heaven sent miracles!

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Tuesday, March 13th 2012, 9:45pm

Hi there TL

I was on metformin to sort out a blood clotting issue as it also works to correct a PAI-1 positive condition, as well as assist in PCOS & diabetes. What a marvellous multi functional drug :snigger:


Me 40 DH 35 TTC 10yr
peritoneal mesothelioma, cystectomy 97 & 00
peritonectomy, lost both tubes & most of left ovary Aug 07

Dec 07 BFP b/ov m/c 9.6wk
July 08 BFN
Dec 08 BFP b/ov m/c 9.6wk

July 09 BFN
Nov 09 BFP 2 x sacs 1 b/o 1 no hrtbt m/c 9.2wk
May10 BFP at 8+4 m/mc @10wk scan ERPC

Found: High NK cells, DQ Alpha match, LAD neg & PAI-1 pos...

NOV 2010 - Immune IVF at CARE Manchester
:BFP: [zx076] :girl: born 25/8/11

OCT 2012 - Immune IVF at CARE Manchester
:BFP: [zx076] :boy: born 24/6/13



Posts: 3

Reg: Mar 16th 2012

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Friday, March 16th 2012, 12:58pm

Hi Tigerlilly,

I was put on metformin before my 3rd IVF cycle because of PCOS,

When I was oon the stimms I overstimulated alot...84 follicles..

10 embryos frozen in St Marys Manchester :biggrin:

i too got OHSS and was in hospital for 2 weeks :thumbdown:

I always thought metformin was for diabetics but the nurse explained that it helps with PCOS and the follicles that you do produce are better quality.

hope this of luck to you hun xx

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