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  • "Diaemus" started this thread

Posts: 556

Reg: Aug 9th 2009

Location: Wales

Children: None, M/C Nov 08; M/C May 09; M/C June 10

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1

Thursday, June 16th 2011, 11:36pm

poor responders and immunology

Hi Guys,
I have had 2 normal IVF cycles done and had a poor response to stimms on both ( 1 or 2 follies). From what I've been reading a immunological issue can cause this to happen. Has anyone heard of this or been in this situation and had a successful immunology protocol?
Ta for any responses.
TTC 14yrs
Clomid x 6 BFN's
4 BFPs m/c's
2x IVF - poor response
NK CD19+/CD5+
Immune IVF -ve
Immune IVF +ve, m/c
3/16Hashimotos''s and peri-menopausal

Maria72

MODERATOR

    Italy

Posts: 13,772

What's Up?
ohffs

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2

Friday, June 17th 2011, 5:45am

Hi
I am a poor responder with immune issues. But there are also normal responders with immune issues.

    United Kingdom

Posts: 3,648

Reg: Jul 2nd 2009

Location: Suffolk

Children: Beautiful Jessica Mae x Holly and Elliot!

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3

Friday, June 17th 2011, 5:48am

...........and I am a poor responder with no known immune issues - sorry, it's never easy as we don't fit into boxes! Have you had Day 2 bloods taken and an AMH test done?

hx
3 X ICSI
Jessica Mae Duffety born sleeping on 9 January 2011 (21+2) - TS and HLHS
Holly and Elliot Duffety born on 16 October 2011 (25+6)
Natural Surprise - Matthew Evan Duffety born sleeping on 11 October 2013 (15+5)

    United Kingdom

Posts: 330

Reg: Feb 18th 2011

Location: Italy

Children: Our miracle baby is on it's way!

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4

Friday, June 17th 2011, 10:01am

Hi, I am a poor responder and have known immune issues. Immune issues can affect egg quality. I followed an immune protocol (and still am) and as you can see from my signature, I am 5 weeks tomorrow. xx

AMH 8.4 (me=36). 6 cycles clomid. Immune issues.
1st IVF cycle April 11 - canx due to endo cyst.
2nd IVF cycle with immune meds May 11 :BFP: [zx076] seen 5wk5d, 8wk5d, 12wk
"There can be miracles when you believe"
My diary


chatterbox

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Posts: 8,584

Reg: Nov 30th 2007

Children: Two heaven sent miracles!

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5

Friday, June 17th 2011, 1:24pm

Hi hun, yep I'm an immuney who was also a poor responder. There is a link between the two which 'can' start in follicular fluid.

That said I also believe it can depend on the protocol and even the particular month and how your body decides to respond. My best cycle (egg wise) was on steroids alone with low dose stimms!!! So figure that one :smile: Though best outcome was on full immune protocol.
xxx

Me 40 DH 35 TTC 10yr
peritoneal mesothelioma, cystectomy 97 & 00
peritonectomy, lost both tubes & most of left ovary Aug 07


Dec 07 BFP b/ov m/c 9.6wk
July 08 BFN
Dec 08 BFP b/ov m/c 9.6wk

July 09 BFN
Nov 09 BFP 2 x sacs 1 b/o 1 no hrtbt m/c 9.2wk
May10 BFP at 8+4 m/mc @10wk scan ERPC

Found: High NK cells, DQ Alpha match, LAD neg & PAI-1 pos...

NOV 2010 - Immune IVF at CARE Manchester
:BFP: [zx076] :girl: born 25/8/11

OCT 2012 - Immune IVF at CARE Manchester
:BFP: [zx076] :boy: born 24/6/13

  • "Diaemus" started this thread

Posts: 556

Reg: Aug 9th 2009

Location: Wales

Children: None, M/C Nov 08; M/C May 09; M/C June 10

Thanks: 1 / 0

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6

Friday, June 17th 2011, 7:18pm

Cheers guys. That's my biggest fear. That because I am a poor responder I won't respond to the immune protocol........if they decide I need it.

Chatterbox, can't believe you've only a couple of months to go : D
TTC 14yrs
Clomid x 6 BFN's
4 BFPs m/c's
2x IVF - poor response
NK CD19+/CD5+
Immune IVF -ve
Immune IVF +ve, m/c
3/16Hashimotos''s and peri-menopausal

chatterbox

Megastar

Posts: 8,584

Reg: Nov 30th 2007

Children: Two heaven sent miracles!

Thanks: 36 / 16

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7

Monday, June 20th 2011, 9:59am

Nope, if anything it may actually give you a good chance! :D

Me 40 DH 35 TTC 10yr
peritoneal mesothelioma, cystectomy 97 & 00
peritonectomy, lost both tubes & most of left ovary Aug 07


Dec 07 BFP b/ov m/c 9.6wk
July 08 BFN
Dec 08 BFP b/ov m/c 9.6wk

July 09 BFN
Nov 09 BFP 2 x sacs 1 b/o 1 no hrtbt m/c 9.2wk
May10 BFP at 8+4 m/mc @10wk scan ERPC

Found: High NK cells, DQ Alpha match, LAD neg & PAI-1 pos...

NOV 2010 - Immune IVF at CARE Manchester
:BFP: [zx076] :girl: born 25/8/11

OCT 2012 - Immune IVF at CARE Manchester
:BFP: [zx076] :boy: born 24/6/13




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